Michael Clague
My training took me from rotational diffusion in membranes, to virus fusion, to cell biology. On appointment at University of Liverpool, my first steps were taken in phosphoinositide regulation of endosomal membrane dynamics, most notably we discovered the substrate specificity of the the myotubularin family lipid phosphatases. More recently, ubiquitin biology, with a focus on the deubiquitylating enzymes and putting them on the map as drug targets. Currently I am interested in organelle quality control, with a side hustle on immune checkpoint receptor trafficking. I also like numbers.
Abstracts this author is presenting: