Sylvie Callegari 49th Lorne Conference on Protein Structure and Function 2024

Sylvie Callegari

Dr. Sylvie Callegari is a recently appointed lab head at WEHI, studying the role of ubiquitin in mitochondrial quality control. Dr Callegari completed her PhD at the University of South Australia before moving to Göttingen, Germany for a postdoctoral position in mitochondrial biochemistry in the lab of Prof. Peter Rehling, where she focussed on mitochondrial quality control and protein import into mitochondria. In 2019, she joined Prof. David Komander's lab (WEHI) as a Senior Research Officer, where she led the team that uncovered the structure and activation mechanism of the Parkinson’s disease-linked protein PINK1 that acts as a beacon for mitochondrial damage (Callegari et al. Science 2025), for which the team were awarded the 2025 Eureka Prize for Scientific Discovery.

Abstracts this author is presenting: